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In Vivo evaluation of gold nanoparticles functionalized with Arthrospira platensis protein extract
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| dc.contributor.author | RUDI, Ludmila | |
| dc.contributor.author | CHIRIAC, Tatiana | |
| dc.contributor.author | ZINICOVSCAIA, Inga | |
| dc.contributor.author | CEPOI, Liliana | |
| dc.contributor.author | GROZDOV, Dmitrii | |
| dc.date.accessioned | 2026-03-31T19:02:20Z | |
| dc.date.available | 2026-03-31T19:02:20Z | |
| dc.date.issued | 2026 | |
| dc.identifier.citation | RUDI, Ludmila; Tatiana CHIRIAC; Inga ZINICOVSCAIA; Liliana CEPOI and Dmitrii GROZDOV. In Vivo evaluation of gold nanoparticles functionalized with Arthrospira platensis protein extract. One Health and Risk Management. 2026, vol. 7, nr. 1, pp. 4-14. ISSN 2587-3458. | en_US |
| dc.identifier.issn | 2587-3458 | |
| dc.identifier.uri | https://www.doi.org/10.38045/ohrm.2026.1.01 | |
| dc.identifier.uri | https://repository.utm.md/handle/5014/35877 | |
| dc.description | Access full text: https://www.doi.org/10.38045/ohrm.2026.1.01 | en_US |
| dc.description.abstract | Gold nanoparticles (AuNPs) have gained increasing attention in nanomedicine due to their biocompatibility and unique physicochemical properties, which make them suitable for targeted therapies against cancer and other chronic diseases. Functionalizing AuNPs with bioactive compounds further enhances their biocompatibility and therapeutic potential. This study aimed to evaluate the effects of 10 nm citrate-stabilized AuNPs functionalized with a protein extract from Arthrospira platensis (AuNPs-APE) on biodistribution, as well as hematological and biochemical parameters, in Wistar rats. | en_US |
| dc.description.abstract | Nanoparticulele de aur (AuNP) sunt utilizate tot mai frecvent în nanomedicină datorită biocompatibilității și proprietăților fizico-chimice unice, care le susțin aplicabilitatea în terapiile țintite pentru cancer și boli cronice. Funcționalizarea cu ajutorul compușilor bioactivi le optimizează potențialul terapeutic și biocompatibilitatea. Acest studiu a evaluat efectele funcționalizării AuNP stabilizate cu citrat de 10 nm, cu un extract proteic din Arthrospira platensis (AuNP-APE) asupra biodistribuției, profilurilor hematologic și biochimic la șobolani Wistar. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Moldavian Biosafety and Biosecurity Association (MDBBA) | en_US |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
| dc.subject | gold nanoparticles | en_US |
| dc.subject | arthrospira platensis | en_US |
| dc.subject | protein extract | en_US |
| dc.subject | wistar rats | en_US |
| dc.subject | biodistribution | en_US |
| dc.subject | hematological assessment | en_US |
| dc.subject | biochemical profile | en_US |
| dc.subject | nanoparticule de aur | en_US |
| dc.subject | extract proteic | en_US |
| dc.subject | şobolani wistar | en_US |
| dc.subject | biodistribuţie | en_US |
| dc.subject | evaluare hematologică | en_US |
| dc.subject | profil biochimic | en_US |
| dc.title | In Vivo evaluation of gold nanoparticles functionalized with Arthrospira platensis protein extract | en_US |
| dc.title.alternative | Evaluarea In Vivo a nanoparticulelor de aur funcționalizate cu extract proteic din Arthrospira platensis | en_US |
| dc.type | Article | en_US |
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